As a result, American women sometimes rely on custom-compounded testosterone prescriptions that may deliver much higher doses than the Australian product and raise women's testosterone to levels higher than normal, potentially producing untoward side effects.
After 21 days of daily administration, the 5-mg dose brought postmenopausal women's peak blood levels of total testosterone right into the normal premenopausal range—with a peak slightly above the upper limit of the premenopause normal and 24-hour average to slightly below the limit.
For women after menopause, it took 5 mg, the lowest dose of this product, to raise testosterone back to a premenopause level. The 10-mg dose raised testosterone levels to a higher peak but only somewhat higher than the norm (50%) over 24 hours. Researchers from Monash University in Melbourne and the University of South Australia in Adelaide tested two different doses of the testosterone cream product known as AndroFeme (5 mg and 10 mg doses. Since custom-compounded formulations are not FDA approved and are not routinely checked for dose content, it is difficult to know how a given formulation will affect women's testosterone levels.
A new pharmacokinetics study of a brand of testosterone cream for women approved in Western Australia has been published online in Menopause, the journal of The North American Menopause Society (NAMS. Women should be cautious about what dose of testosterone they are receiving and whether they really need it. In the United States we do not yet have an approved testosterone product designed for women," says NAMS Executive Director Margery Gass.
For more information here article source Source: The North American Menopause Society (NAMS)
After 21 days of daily administration, the 5-mg dose brought postmenopausal women's peak blood levels of total testosterone right into the normal premenopausal range—with a peak slightly above the upper limit of the premenopause normal and 24-hour average to slightly below the limit.
For women after menopause, it took 5 mg, the lowest dose of this product, to raise testosterone back to a premenopause level. The 10-mg dose raised testosterone levels to a higher peak but only somewhat higher than the norm (50%) over 24 hours. Researchers from Monash University in Melbourne and the University of South Australia in Adelaide tested two different doses of the testosterone cream product known as AndroFeme (5 mg and 10 mg doses. Since custom-compounded formulations are not FDA approved and are not routinely checked for dose content, it is difficult to know how a given formulation will affect women's testosterone levels.
A new pharmacokinetics study of a brand of testosterone cream for women approved in Western Australia has been published online in Menopause, the journal of The North American Menopause Society (NAMS. Women should be cautious about what dose of testosterone they are receiving and whether they really need it. In the United States we do not yet have an approved testosterone product designed for women," says NAMS Executive Director Margery Gass.
For more information here article source Source: The North American Menopause Society (NAMS)
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